Endocrine Abstracts

Objective: Insulin resistance (IR) has been reported in first-degree male relatives of patients with IC (FDMR). Retinol binding protein-4 (RBP4) has been shown to be increased in IR. We hypothesized that RBP4 would be: 1) increased in FDMR compared with controls and 2) correlated with features of IR.Methods: The study was approved by Leeds (West) Research Ethics Committee. We measured RBP4 in 162 healthy FDMR previously found to be more insulin resistant...